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一年一度的全球肿瘤界盛会-美国临床肿瘤学会(ASCO)年会将于当地时间6月2日-6月6日召开。ASCO年会是世界上规模最大、学术水平最高、最具权威的临床肿瘤学会议,致力于癌症的预防、治疗和改善患者管理,以展示肿瘤的基础研究和临床最新研究为特点,讨论当前国际先进的治疗方法。随着中国临床研究在肿瘤领域的快速成长,中国在世界肿瘤领域中也发挥着日益重要的作用。此次会议上,中国大陆研究Oral Abstract Session入选16项,另外Clinical Science Symposium和Rapid Abstract Session部分各有1项中国研究入选,共18项。% s4 B$ f6 g0 k
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Developmental Therapeutics—Immunotherapy
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. s' t& s* _; ~3 O4 k摘要号:2507 标题:Phase I study of the bifunctional anti-PD-L1/TGF-βRII agent SHR-1701 combined with SHR2554, an EZH2 inhibitor, in patients with previously treated advanced lymphoma and solid tumors. 报告人:丰恺超 单位:JFJ总医院第一医学中心 5 G; X4 F( \$ |4 v$ ?% x# ?7 v2 v
在研疗法-分子靶向药物和肿瘤生物学
0 D# E' T' a9 \! B2 B* m, I+ f Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
# K+ v" f! y# x; |9 Y4 c' v摘要号:3001 标题:BL-B01D1, a first-in-class EGFRxHER3 bispecific antibody-drug conjugate (ADC), in patients with locally advanced or metastatic solid tumor: Results from a first-in-human phase 1 study. 报告人:张力 单位:中山大学肿瘤防治中心 $ c) F$ o" J8 W7 k& C9 F( y a
摘要号:3007 标题:A phase I study of KL590586, a next-generation selective RET inhibitor, in patients with RET-altered solid tumors. 报告人:周清 单位:广东省人民医院 , J- q& l0 P } [% ~, A6 `
胃肠道肿瘤-结直肠癌和肛门癌
1 F1 t* d3 R3 v: I! f/ p2 e- B Gastrointestinal Cancer—Colorectal and Anal 摘要号:3505 标题:Long-term outcome of neoadjuvant mFOLFOX6 with or without radiation versus fluorouracil plus radiation for locally advanced rectal cancer: A multicenter, randomized phase III trial. 报告人:张剑威 单位:中山大学附属第六医院
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胃肠道肿瘤-胃食管癌、胰腺癌和肝胆癌 Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary 4 Z# d# Z2 k& w6 ]
摘要号:4001 标题:Perioperative PD-1 antibody toripalimab plus SOX or XELOX chemotherapy versus SOX or XELOX alone for locally advanced gastric or gastro-oesophageal junction cancer: Results from a prospective, randomized, open-label, phase II trial. 报告人:袁庶强 单位:中山大学肿瘤防治中心 - |( @$ `0 u& F* r& D. B
妇科肿瘤 Gynecologic Cancer
+ C. w# q: ^ u) s摘要号:5516 标题:Camrelizumab plus apatinib in patients with advanced or recurrent endometrial cancer after failure of at least one prior systemic therapy: A single-arm phase II trial. 报告人:田文娟 单位:复旦大学附属肿瘤医院 " X" G- Z/ @0 i1 w, M
头颈肿瘤
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摘要号:6000 标题:Concurrent chemoradiotherapy followed by adjuvant cisplatin-gemcitabine versus cisplatin-5-fluorouracil chemotherapy for N2-3 nasopharyngeal carcinoma: A multicentre, open-label, randomised, controlled, phase 3 trial. 报告人:唐林泉 单位:中山大学肿瘤防治中心
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摘要号:6001 标题:Induction chemotherapy plus radiotherapy alone versus cisplatin-based concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma: An open-label, non-inferiority, randomized phase 3 trial. 报告人:陈明远 单位:中山大学肿瘤防治中心 # N& P# k# H7 J9 b' d* u
摘要号:LBA6002 标题:PD-1 blockade with sintilimab plus induction chemotherapy and concurrent chemoradiotherapy (IC-CCRT) versus IC-CCRT in locoregionally-advanced nasopharyngeal carcinoma (LANPC): A multicenter, phase 3, randomized controlled trial (CONTINUUM). 报告人:马骏 单位:中山大学肿瘤防治中心
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血液系统恶性肿瘤-淋巴瘤和慢性淋巴细胞白血病 Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia j0 l, e5 ^9 \! |% z' A
摘要号:7503 标题:Golidocitinib in treating refractory or relapsed peripheral T-cell lymphoma: Primary analysis of the multinational pivotal study results (JACKPOT8). 报告人:蔡清清 单位:中山大学肿瘤防治中心
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血液系统恶性肿瘤-浆细胞疾病, L& U& M* p! q+ N
Hematologic Malignancies—Plasma Cell Dyscrasia 5 }' r, W( K0 ?
摘要号:8005 标题:Updated results of a phase I, open-label study of BCMA/CD19 dual-targeting fast CAR-T GC012F for patients with relapsed/refractory multiple myeloma (RRMM). 报告人:杜鹃 单位:上海长征医院 3 ]; [9 v7 l% |
肺癌-非小细胞局部-区域性/小细胞/其他胸部肿瘤
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% A; x7 s& H/ R( |( P7 I5 E5 K摘要号:8501 标题:Perioperative toripalimab + platinum-doublet chemotherapy vs chemotherapy in resectable stage II/III non-small cell lung cancer (NSCLC): Interim event-free survival (EFS) analysis of the phase III NEOTORCH study. 报告人:陆舜 单位:上海交通大学医学院附属胸科医院
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肺癌-转移性非小细胞肺癌
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& i% P2 L. l4 }. A摘要号:9001 标题:Randomized phase 3 study of first-line AZD3759 (zorifertinib) versus gefitinib or erlotinib in EGFR-mutant (EGFRm+) non–small-cell lung cancer (NSCLC) with central nervous system (CNS) metastasis. 报告人:吴一龙 单位:广东省人民医院 , L" x) T! Y- S" }" E
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摘要号:9002 标题:Sunvozertinib for the treatment of NSCLC with EGFR Exon20 insertion mutations: The first pivotal study results. 报告人:王孟昭 单位:北京协和医院
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摘要号:9003 标题:Final overall survival and biomarker analyses of CHOICE-01: A double-blind randomized phase 3 study of toripalimab versus placebo in combination chemotherapy for advanced NSCLC without EGFR/ALK mutations. 报告人:邬麟 单位:湖南省肿瘤医院 $ n" Z* E2 P3 M) L. {$ e' ~
黑色素瘤/皮肤癌
# u8 n4 s' R; w2 N) a Melanoma/Skin Cancers 摘要号:9508 标题:Temozolomide plus cisplatin versus toripalimab (anti-PD-1) as adjuvant therapy in resected mucosal melanoma. 报告人:郭军 单位:北京大学肿瘤医院 - ?0 u* `8 h1 q3 ~% l9 W
快速摘要报告
0 M- t/ U4 b9 ?. b! V. m Rapid Abstract Session 摘要号:LBA1013 标题:TORCHLIGHT: a randomized, double-blind, phase III trial of toripalimab versus placebo, in combination with nab-paclitaxel(nab-P) for patients with metastatic or recurrent triple-negative breast cancer (TNBC). 报告人:江泽飞 单位:JFJ总医院第五医学中心
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临床科学研讨会" C% q- }" L0 ~" \& `4 f
Clinical Science Symposium 摘要号:11510 标题:The clinical value of tumor-informed minimal residual disease detection in sarcoma. 报告人:尹军强 单位:中山大学附属第一医院 0 }5 k& [6 ?3 g v( r2 X! p" Q
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