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北京时间2025年9月18日，国际权威医学期刊《新英格兰医学杂志》（The New England Journal of Medicine）在线发表一项重要医学突破——中国科学技术大学附属第一医院（安徽省立医院）（以下简称“中国科大附一院”）风湿免疫科主任陈竹教授团队成功开展全球首次基于脂质纳米颗粒（LNP）体内嵌合抗原受体T细胞疗法（CAR-T）治疗系统性红斑狼疮（SLE）临床研究，并取得阶段性关键进展。4 D# n/ w; m3 H
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https://www.nejm.org/doi/full/10.1056/NEJMc2509522
4 E/ G: ~" ~5 D/ AIn Vivo CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus9 Z. _4 U; q( U& _3 X* u
文章类型：correspondence（research letter）
# O. o# ~% n2 C9 w6 {7 nQian Wang, M.D.
* ^; ^) |7 o+ d, ?% k( gFirst Affiliated Hospital of University of Science and Technology of China, Hefei
/ P; M8 F! J, _- i* hZe Xiu Xiao, M.D.! M$ g0 Y/ n7 R; d2 j
Shenzhen MagicRNA Biotechnology, Shenzhen, China
2 R( N. p- G0 w2 Z, f% w6 a; AXu Zheng, M.D.5 V1 b/ j, w; b$ V) g
First Affiliated Hospital of University of Science and Technology of China, Hefei
+ u! w1 C, Y+ G2 MGuihong Wang, M.D.3 y; T; F3 y7 i& V3 G
Anqing Municipal Hospital, Anqing, China
g' t8 i$ R; f: h1 ^Linlin Yang, M.S., b9 f g \3 l8 j
Anhui University of Science and Technology, Huainan, China
4 E+ Y# L- G; a" J% P( S: oLina Shi, Ph.D.% A, k: V3 Q$ Q! {
Shenzhen MagicRNA Biotechnology, Shenzhen, China+ c& u2 ~% Y3 v; |6 N9 k) W
Nan Xiang, M.D.- l v; p' r2 D" [' D! I
Xingbing Wang, M.D.
5 }) K2 H# `1 U$ r3 B6 Q% C+ G; N7 oFirst Affiliated Hospital of University of Science and Technology of China, Hefei
; f' B# V) e- ]( e0 a0 x1 X' I* S9 UGao-Feng Zha, Ph.D.
) z- S7 o ~) Z% U7 a0 TShenzhen MagicRNA Biotechnology, Shenzhen, China& q3 Y7 k# i6 J7 k
Georg Schett, M.D.' I) Y- Y3 k" S w/ ?: W
Friedrich-Alexander-University Erlangen–Nuremberg, Erlangen, Germany
6 n2 ^2 e" b- E* j* y7 xZhu Chen, M.D. https://orcid.org/0000-0003-0828-1583
1 E( {) [ n; j6 ^First Affiliated Hospital of University of Science and Technology of China, Hefei |
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发表于 2025-8-22 10:42:11
楼主
到年底再说吧