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北京时间2025年9月18日，国际权威医学期刊《新英格兰医学杂志》（The New England Journal of Medicine）在线发表一项重要医学突破——中国科学技术大学附属第一医院（安徽省立医院）（以下简称“中国科大附一院”）风湿免疫科主任陈竹教授团队成功开展全球首次基于脂质纳米颗粒（LNP）体内嵌合抗原受体T细胞疗法（CAR-T）治疗系统性红斑狼疮（SLE）临床研究，并取得阶段性关键进展。1 C8 Z. x! N+ {9 |; h( {
, M( @/ a: R, g! Z0 S0 V4 l- xhttps://www.nejm.org/doi/full/10.1056/NEJMc25095225 p7 U; U" T: o" l
In Vivo CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus
9 [8 c9 ?; v( c* p$ N8 |文章类型：correspondence（research letter）
4 d( S) O. q4 H% O. a5 vQian Wang, M.D., K& u/ ^4 Z/ S6 M4 M
First Affiliated Hospital of University of Science and Technology of China, Hefei4 H v8 @6 l! D, |
Ze Xiu Xiao, M.D.
% Z0 f% X9 |! a6 c. o' o+ m9 `Shenzhen MagicRNA Biotechnology, Shenzhen, China
7 f! A& o) T, F: g- V' \/ j1 oXu Zheng, M.D.1 C6 n+ P5 J, U
First Affiliated Hospital of University of Science and Technology of China, Hefei2 ?. d% h+ `: h
Guihong Wang, M.D.
3 f/ t7 _. P* C4 B" t; N9 R6 @/ qAnqing Municipal Hospital, Anqing, China
! Z9 S9 A) b! @1 W5 QLinlin Yang, M.S.
. B# ^" Z! N; U; v; b ]) D5 a! |Anhui University of Science and Technology, Huainan, China8 w6 O+ x: ]# G' x( J6 c( B4 v
Lina Shi, Ph.D.! U" j0 l4 ` u9 J* ^) j/ b! }0 _
Shenzhen MagicRNA Biotechnology, Shenzhen, China- n/ s7 q$ U; `7 T2 P
Nan Xiang, M.D.6 n# Z5 p* ?( ?. Q- `1 L
Xingbing Wang, M.D.3 n: r. o" l' x9 B
First Affiliated Hospital of University of Science and Technology of China, Hefei, J: v' O) P# I. F. X/ o
Gao-Feng Zha, Ph.D.
- R( O% f0 ~! S- Z" }9 K' UShenzhen MagicRNA Biotechnology, Shenzhen, China
`& I2 s& Z/ i3 G& i' E* W2 BGeorg Schett, M.D.
: I, }. z9 b' t9 r. x/ ^5 s. EFriedrich-Alexander-University Erlangen–Nuremberg, Erlangen, Germany# o- e+ c1 S; Q# [, }) H
Zhu Chen, M.D. https://orcid.org/0000-0003-0828-15836 k+ b# n# j8 q/ l* R5 j
First Affiliated Hospital of University of Science and Technology of China, Hefei |
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发表于 2025-8-22 10:42:11
楼主
到年底再说吧